EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level  |
|---|
    2.7.4.14 | 5'-nucleotidase deficiency |
3036196 |
Pyrimidine nucleoside monophosphate kinase hyperactivity in hereditary erythrocyte pyrimidine 5'-nucleotidase deficiency. |
causal interaction
unassigned |
3
0 |
| 2.7.4.14 | Abortion, Missed |
32323732 |
Pigment epithelium?derived factor facilitates NLRP3 inflammasome activation through downregulating cytidine monophosphate kinase 2: A potential treatment strategy for missed abortion. |
causal interaction
therapeutic application
unassigned |
1
4
0 |
| 2.7.4.14 | Acquired Immunodeficiency Syndrome |
15163660 |
Substrate-induced conformational changes in human UMP/CMP kinase. |
ongoing research
unassigned |
4
0 |
| 2.7.4.14 | Acute Lung Injury |
34037470 |
MiR-494-3p alleviates acute lung injury through regulating NLRP3 activation by targeting CMPK2. |
unassigned |
0 |
| 2.7.4.14 | Atherosclerosis |
33874983 |
Mitochondrial protein CMPK2 regulates IFN alpha-enhanced foam cell formation, potentially contributing to premature atherosclerosis in SLE. |
causal interaction
diagnostic usage
ongoing research
unassigned |
2
3
2
0 |
| 2.7.4.14 | Bacterial Infections |
33186560 |
CMPK2 of triploid crucian carp is involved in immune defense against bacterial infection. |
unassigned |
0 |
| 2.7.4.14 | Breast Neoplasms |
27558661 |
Prognostic significance of nuclear expression of UMP-CMP kinase in triple negative breast cancer patients. |
diagnostic usage
unassigned |
4
0 |
| 2.7.4.14 | Breast Neoplasms |
34438242 |
Potential role of CMPK1, SLC29A1, and TLE4 polymorphisms in gemcitabine-based chemotherapy in HER2-negative metastatic breast cancer patients: pharmacogenetic study results from the prospective randomized phase II study of eribulin plus gemcitabine versus paclitaxel plus gemcitabine (KCSG-BR-13-11). |
ongoing research
therapeutic application
unassigned |
2
4
0 |
| 2.7.4.14 | Carcinoma, Hepatocellular |
179702 |
Differences between pyrimidine nucleoside monophosphate kinase from rat Novikoff ascites hepatoma and rat liver. |
ongoing research
unassigned |
3
0 |
| 2.7.4.14 | Carcinoma, Hepatocellular |
211381 |
Pyrimidine nucleoside monophosphate kinase from rat liver and rat Novikoff ascites hepatoma (EC 2.7.4.14). |
ongoing research
unassigned |
1
0 |
