EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
2.3.1.39 | Aberrant Crypt Foci |
19173288 |
Fatty acid synthase is over-expressed in large aberrant crypt foci in rats treated with azoxymethane. |
causal interaction therapeutic application unassigned |
3 1 0 |
2.3.1.39 | Aberrant Crypt Foci |
19358283 |
Increased expression of fatty acid synthase in human aberrant crypt foci: possible target for colorectal cancer prevention. |
causal interaction diagnostic usage unassigned |
3 3 0 |
2.3.1.39 | Acidosis |
15523670 |
In support of fatty acid synthase (FAS) as a metabolic oncogene: extracellular acidosis acts in an epigenetic fashion activating FAS gene expression in cancer cells. |
causal interaction ongoing research unassigned |
1 3 0 |
2.3.1.39 | Acute Coronary Syndrome |
23305094 |
Effects of soluble epoxide hydrolase inhibitor on the expression of fatty acid synthase in peripheral blood mononuclear cell in patients with acute coronary syndrome. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 4 4 |
2.3.1.39 | Acute Lung Injury |
31287803 |
Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity. |
causal interaction ongoing research therapeutic application unassigned |
4 2 2 0 |
2.3.1.39 | Adenocarcinoma |
11176534 |
Fatty acid synthase: an early molecular marker of progression of prostatic adenocarcinoma to androgen independence. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 3 1 |
2.3.1.39 | Adenocarcinoma |
15051923 |
Liver-type fatty acid-binding protein is highly expressed in intestinal metaplasia and in a subset of carcinomas of the stomach without association with the fatty acid synthase status in the carcinoma. |
causal interaction diagnostic usage ongoing research therapeutic application |
3 3 3 1 |
2.3.1.39 | Adenocarcinoma |
15094777 |
Inhibition of tumor-associated fatty acid synthase activity antagonizes estradiol- and tamoxifen-induced agonist transactivation of estrogen receptor (ER) in human endometrial adenocarcinoma cells. |
causal interaction diagnostic usage ongoing research therapeutic application |
4 3 2 1 |
2.3.1.39 | Adenocarcinoma |
16084671 |
Increased ratio of saturated to unsaturated C18 fatty acids in colonic adenocarcinoma: implications for cryotherapy and lipid raft function. |
causal interaction therapeutic application unassigned |
4 2 0 |
2.3.1.39 | Adenocarcinoma |
16564913 |
Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma. |
causal interaction therapeutic application unassigned |
4 1 0 |