EC Number   |
Disease |
PubMed ID |
Title of Publication  |
Category |
Confidence Level |
|---|
   3.4.22.53 | Carcinoma, Hepatocellular |
21861846 |
Apoptosis by aloe-emodin is mediated through downregulation of calpain-2 and ubiquitin-protein ligase E3A in human hepatoma Huh-7 cells. |
unassigned |
0 |
| 3.4.22.53 | Leukemia |
16865282 |
Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
4
0 |
| 3.4.22.53 | Prostatic Neoplasms |
16865282 |
Apoptosis induced by novel aldehyde calpain inhibitors in human tumor cell lines. |
causal interaction
ongoing research
therapeutic application
unassigned |
4
4
4
0 |
| 3.4.22.53 | Neoplasms |
18839313 |
Apoptosis-related genes change their expression with age and hearing loss in the mouse cochlea. |
unassigned |
0 |
| 3.4.22.53 | Arthritis |
7632090 |
Appearance of calpain correlates with arthritis and cartilage destruction in collagen induced arthritic knee joints of mice. |
causal interaction
diagnostic usage
ongoing research
therapeutic application |
2
2
3
1 |
| 3.4.22.53 | Stomach Neoplasms |
23958790 |
Artesunate inhibits the growth of gastric cancer cells through the mechanism of promoting oncosis both in vitro and in vivo. |
ongoing research
therapeutic application
unassigned |
3
1
0 |
| 3.4.22.53 | Craniocerebral Trauma |
17612919 |
Attenuation of microtubule associated protein-2 degradation after mild head injury by mexiletine and calpain-2 inhibitor. |
ongoing research
therapeutic application
unassigned |
3
2
0 |
| 3.4.22.53 | Head Injuries, Closed |
17612919 |
Attenuation of microtubule associated protein-2 degradation after mild head injury by mexiletine and calpain-2 inhibitor. |
ongoing research
therapeutic application
unassigned |
3
2
0 |
| 3.4.22.53 | Psoriasis |
15654835 |
Autoantibodies directed against the protease inhibitor calpastatin in psoriasis. |
diagnostic usage
ongoing research
therapeutic application
unassigned |
1
4
4
0 |
| 3.4.22.53 | Neoplasms |
31000696 |
Baicalein inhibits fibronectin-induced epithelial-mesenchymal transition by decreasing activation and upregulation of calpain-2. |
ongoing research
unassigned |
3
0 |
