EC Number |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
---|
3.4.18.1 | Carcinogenesis |
23800510 |
Cathepsin proteases promote angiogenic sprouting and laser-induced choroidal neovascularisation in mice. |
causal interaction unassigned |
2 0 |
3.4.18.1 | Carcinoma |
15162377 |
Up-regulation of cathepsin X in prostate cancer and prostatic intraepithelial neoplasia. |
causal interaction diagnostic usage therapeutic application unassigned |
4 4 1 0 |
3.4.18.1 | Carcinoma |
16025436 |
Up-regulation of cathepsin X in Helicobacter pylori gastritis and gastric cancer. |
causal interaction diagnostic usage ongoing research unassigned |
3 1 4 0 |
3.4.18.1 | Carcinoma, Hepatocellular |
21966391 |
Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma. |
causal interaction diagnostic usage ongoing research unassigned |
4 3 3 0 |
3.4.18.1 | Cardiovascular Diseases |
32928870 |
Deciphering the Plasma Proteome of Type 2 Diabetes. |
causal interaction diagnostic usage ongoing research unassigned |
3 3 3 0 |
3.4.18.1 | cathepsin x deficiency |
1920915 |
Acid carboxypeptidase deficiency in galactosialidosis. |
causal interaction unassigned |
4 0 |
3.4.18.1 | cathepsin x deficiency |
20133781 |
Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice. |
ongoing research therapeutic application unassigned |
1 1 0 |
3.4.18.1 | cathepsin x deficiency |
21616554 |
Cellular senescence induced by cathepsin X downregulation. |
causal interaction diagnostic usage therapeutic application unassigned |
4 3 1 0 |
3.4.18.1 | cathepsin x deficiency |
23152410 |
IGF-I receptor phosphorylation is impaired in cathepsin X-deficient prostate cancer cells. |
causal interaction therapeutic application unassigned |
4 1 0 |
3.4.18.1 | Cholangitis |
30087368 |
Increased expression and altered localization of cathepsin Z are associated with progression to jaundice stage in primary biliary cholangitis. |
causal interaction diagnostic usage unassigned |
1 3 0 |