EC Number   |
Disease |
PubMed ID |
Title of Publication |
Category |
Confidence Level |
|---|
    1.18.1.6 | Neoplasms |
14614330 |
Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2. |
unassigned |
0 |
| 1.18.1.6 | Neoplasms |
18319262 |
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells. |
causal interaction
therapeutic application
unassigned |
3
2
0 |
| 1.18.1.6 | Neoplasms |
19004824 |
Correlation of fragile histidine triad (Fhit) protein structural features with effector interactions and biological functions. |
unassigned |
0 |
| 1.18.1.6 | Neoplasms |
28747430 |
Ferredoxin reductase is critical for p53-dependent tumor suppression via iron regulatory protein 2. |
causal interaction
unassigned |
3
0 |
| 1.18.1.6 | Neoplasms |
28842474 |
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells. |
therapeutic application
unassigned |
2
0 |
| 1.18.1.6 | Neoplasms |
34090862 |
Ferredoxin reductase regulates proliferation, differentiation, cell cycle and lipogenesis but not apoptosis in SZ95 sebocytes. |
unassigned |
0 |
| 1.18.1.6 | Optic Atrophy |
29040572 |
Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy. |
causal interaction
unassigned |
3
0 |
| 1.18.1.6 | Optic Atrophy |
29554255 |
Biallelic mutations in the ferredoxin reductase gene cause novel mitochondriopathy with optic atrophy. |
causal interaction
unassigned |
3
0 |
| 1.18.1.6 | Tuberculosis |
15863094 |
MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51. |
unassigned |
0 |
| 1.18.1.6 | Vision Disorders |
33742450 |
Report of a case with ferredoxin reductase (FDXR) gene variants in a Chinese boy exhibiting hearing loss, visual impairment, and motor retardation. |
unassigned |
0 |
