EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
6.3.2.9 | -999 |
- |
more |
peptides are synthesized from consensus sequences to evaluate their inhibitory potential against the essential MurD enzyme. The C-7-C mers MurDp1 gives a decrease of MurD ATPase activity with a significant IC50 value of 4 mM. The 12 mers MurDp2 inhibits MurD with an IC50 value of 15 mM |
676300 |
6.3.2.9 | 0.003 |
- |
(R,Z)-2-(3-((2-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)acetamido)methyl)benzamido)pentanedioic acid |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 |
715866 |
6.3.2.9 | 0.005 |
- |
(R,Z)-2-(3-((1-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)formamido)methyl)benzamido)pentanedioic acid |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 |
715866 |
6.3.2.9 | 0.007 |
- |
(R,Z)-2-(3-((3-carboxy-N-(4-((4-oxo-2-thioxothiazolidin-5-ylidene)-methyl)phenyl)propanamido)methyl)benzamido)pentanedioic acid |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 |
715866 |
6.3.2.9 | 0.0084 |
- |
4-[([6-[(4-cyano-2-fluorobenzyl)oxy]naphthalen-2-yl]sulfonyl)amino]benzene-1,3-dicarboxylic acid |
pH 8.6, 37°C |
714902 |
6.3.2.9 | 0.01 |
- |
(2S)-2-[((4-[(Z)-(4-oxo-2-thioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl)carbonyl)amino]pentanedioic acid |
pH not specified in the publication, temperature not specified in the publication |
714905 |
6.3.2.9 | 0.01 |
- |
2,3,4,5-tetrabromo-6-(3,6-dihydroxy-9H-xanthen-9-yl)benzoic acid |
pH 8.0, 37°C |
702636 |
6.3.2.9 | 0.015 |
- |
N-(3-[[(carboxyacetyl)[4-[(Z)-(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]phenyl]amino]methyl]benzoyl)-D-glutamic acid |
pH not specified in the publication, temperature not specified in the publication. Malachite green assay in presence of 0.01% Triton X-100 |
715866 |
6.3.2.9 | 0.03 |
- |
3-bromo-N-(4-([2-(2-naphthylsulfonyl)hydrazono]methyl)phenyl)benzamide |
pH 8.0, 37°C |
694288 |
6.3.2.9 | 0.038 |
- |
2-[([6-[(4-cyano-2-fluorobenzyl)oxy]naphthalen-2-yl]sulfonyl)amino]benzene-1,4-dicarboxylic acid |
pH 8.6, 37°C |
714902 |