EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
3.4.23.45 | 0.0000087 |
- |
(S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-chloropicolinamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000013 |
- |
N-(3-((4S,5S)-2-amino-4-methyl-5-phenyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000014 |
- |
(S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-fluoropicolinamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000021 |
- |
(S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-cyanopicolinamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000028 |
- |
N-(3-((4S,5R)-2-amino-4-methyl-5-phenyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000041 |
- |
Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Stat-Val-Ala-Glu-Phe |
pH 4.5, 37°C, substrate concentration 0.015 mM |
683469 |
3.4.23.45 | 0.000074 |
- |
N-(3-((4S,5R)-2-amino-4-methyl-5-(tetrahydro-2H-pyran-4-yl)-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000078 |
- |
(S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(fluoromethoxy)pyrazine-2-carboxamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000085 |
- |
(S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-methoxypyrazine-2-carboxamide |
pH and temperature not specified in the publication |
754403 |
3.4.23.45 | 0.000102 |
- |
(S)-N-(3-(2-amino-4-methyl-5,6-dihydro-4H-1,3-thiazin-4-yl)-4-fluorophenyl)-5-(difluoromethyl)pyrazine-2-carboxamide |
pH and temperature not specified in the publication |
754403 |