EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    2.7.6.3 | 0.00038 |
- |
5'-(1-[2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl]-2-carboxypiperidine-4-sulfonyl)-5'-deoxyadenosine |
pH 8, 30°C |
760689 |
| 2.7.6.3 | 0.00316 |
- |
2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydro-pteridine-6-carboxylic acid (2-[4-[5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethylsulfanyl]-piperidin-1-yl]-ethyl)-amide |
in 100 mM Tris, pH 8.3, temperature not specified in the publication |
721840 |
| 2.7.6.3 | 0.0051 |
- |
2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydro-pteridine-6-carboxylic acid (2-(2-[5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethanesulfonyl]-thylcarbamoyl)-ethyl)-amide |
pH 8.3, 30°C, recombinant enzyme |
738210 |
| 2.7.6.3 | 0.00953 |
- |
2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carboxylic acid (2-[2-[5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethanesulfonyl]-ethylcarbamoyl]-ethyl)-amide |
in 100 mM Tris, pH 8.3, at 23°C |
721839 |
| 2.7.6.3 | 0.1 |
- |
2-amino-6-[(2-[4-[5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-ylmethylsulfanyl]-piperidin-1-yl]-ethylamino)-methyl]-3H-pteridin-4-one |
IC50 above 0.1 mM, in 100 mM Tris, pH 8.3, temperature not specified in the publication |
721840 |
| 2.7.6.3 | 0.18 |
- |
5'-S-[1-(2-([(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)carbonyl]amino)ethyl)piperidin-4-yl]-5'-thioadenosine |
pH 8.3, 30°C, recombinant enzyme |
738210 |
