EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
2.7.1.48 | 0.00000003463 |
- |
CTP |
at 37°C, pH not specified in the publication |
739129 |
2.7.1.48 | 0.0003214 |
- |
alpinetin |
at 37°C, pH not specified in the publication |
739129 |
2.7.1.48 | 0.0006181 |
- |
flavokawain B |
at 37°C, pH not specified in the publication |
739129 |
2.7.1.48 | 0.0092 |
0.0166 |
N-(4-bromophenyl)-2-[[1-(4-fluorophenyl)-4-hydroxy-1H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]acetamide |
22°C, 20 mM HEPES (pH 7.2), 100 mM KCl, 2 mM MgCl2, 6-300 microM ATP, 6-300 microM uridine, 1-10 nanoM enzyme UCK2 |
758919 |
2.7.1.48 | 0.0164 |
- |
N-(4-bromophenyl)-2-[[1-(4-fluorophenyl)-4-hydroxy-1H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl]acetamide |
pH 8.5, temperature not specified in the publication |
758919 |
2.7.1.48 | 0.0189 |
0.048 |
N-(3,5-dimethylphenyl)-2-[([5-[(4-fluorophenyl)methyl]-7-oxo-2,5,6,7-tetrahydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]methyl)sulfanyl]acetamide |
22°C, 20 mM HEPES (pH 7.2), 100 mM KCl, 2 mM MgCl2, 6-300 microM ATP, 6-300 microM uridine, 1-10 nanoM enzyme UCK2 |
758919 |
2.7.1.48 | 0.031 |
- |
ATP |
pH 8.5, temperature not specified in the publication |
758919 |
2.7.1.48 | 0.048 |
- |
N-(3,5-dimethylphenyl)-2-[([5-[(4-fluorophenyl)methyl]-7-oxo-2,5,6,7-tetrahydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]methyl)sulfanyl]acetamide |
pH 8.5, temperature not specified in the publication |
758919 |
2.7.1.48 | 0.05 |
- |
uridine |
pH 8.5, temperature not specified in the publication |
758919 |
2.7.1.48 | 0.054 |
- |
6-(4-hexyloxyanilino)uracil |
- |
706070 |