EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
    2.5.1.15 | 0.0019 |
- |
4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay, in presence of 2 mM sodium diphosphate |
758913 |
| 2.5.1.15 | 0.0025 |
- |
4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]-N-(pyridin-2-yl)benzene-1-sulfonamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay, in presence of 2 mM sodium diphosphate |
758913 |
| 2.5.1.15 | 0.0034 |
- |
4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]-N-(5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay, in presence of 2 mM sodium diphosphate |
758913 |
| 2.5.1.15 | 0.0081 |
- |
4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay |
758913 |
| 2.5.1.15 | 0.0094 |
- |
4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]-N-(pyrimidin-2-yl)benzene-1-sulfonamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay, in presence of 2 mM sodium diphosphate |
758913 |
| 2.5.1.15 | 0.0113 |
- |
2-amino-6-[[4-(4-aminobenzene-1-sulfonyl)anilino]methyl]pteridin-4(1H)-one |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay, in presence of 2 mM sodium diphosphate |
758913 |
| 2.5.1.15 | 0.0115 |
- |
4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]-N-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay, in presence of 2 mM sodium diphosphate |
758913 |
| 2.5.1.15 | 0.0152 |
- |
4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]-N-(5,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay |
758913 |
| 2.5.1.15 | 0.017 |
- |
2-(7-amino-1-methyl-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)propanoic acid |
at pH 7.6 and 37°C |
737323 |
| 2.5.1.15 | 0.0171 |
- |
N-(4-[[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzene-1-sulfonyl)acetamide |
pH and temperature not specified in the publication, fluorescence polarization based competition binding assay, in presence of 2 mM sodium diphosphate |
758913 |
