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EC Number IC50 Value IC50 Value Maximum Inhibitor Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.760.0000887 - XP620 selective isozyme DGAT1 inhibitor, inhibits the diacylglycerol acyltransferase and the retinol acyltransferase activities at the retinol recognition site, inhibition of 85% of retinyl ester production in intact differentiated Caco-2 cells, IC50: 88.7 nM 658662
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.760.00011 - XP620 inhibits the ARAT activity of acyl coenzyme A:diacylglycerol acyltransferase isozyme 1 dependent on the retinol concentration in vivo and in vitro, IC50: 110 nM, no inhibition of isozyme 2 and acyl coenzyme A:monoacylglycerol acyltransferase isozyme 3, ov 672340
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