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EC Number
IC50 Value
IC50 Value Maximum
Inhibitor
Commentary
Reference
6.3.4.2
0.3
-
CTP
IC50: 0.3 mM
648973
6.3.4.2
0.32
-
CTP
IC50: 0.32 mM
648978
6.3.4.2
0.21
-
CTP
IC50 for the native enzyme: 0.12 in presence of 0.5 mM ATP, 0.22 mM in presence of 1 mM ATP. IC50 for the phosphorylated enzyme: 0.21 mM in presence of 0.5 mM ATP, 0.31 mM in presence of 1 mM ATP
648994
6.3.4.2
0.05
-
CTP
IC50: 0.05 mM
649000
6.3.4.2
0.15
-
CTP
IC50: 0.15 mM
649000
6.3.4.2
0.08
-
8-oxoguanosine
-
674909
6.3.4.2
0.08
-
8-oxoguanosine
IC50 for inhibition of Gln-dependent CTP formation
674909
6.3.4.2
0.11
-
2,6-diaminopurine riboside
IC50 for inhibition of Gln-dependent CTP formation
674909
6.3.4.2
0.11
-
8-oxoguanosine 5'-triphosphate
IC50 for inhibition of Gln-dependent CTP formation
674909
6.3.4.2
0.13
-
8-oxoguanosine
IC50 for inhibition of NH3-dependent CTP formation
674909
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