Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Crystallization (Commentary)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 10 of 10
EC Number Crystallization (Commentary)
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33-
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33hanging drop vapor diffusion method, using 0.25 M sodium formate and 16% (w/v) PEG 3350
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33hanging drop vapour diffusion method using 0.1 M Tris-HCl (pH 8.0), 1.8 M sodium malonate
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33in complex wih adenosine 5'-(beta,gamma-imido)-triphosphate and Mg2+
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33MDD bound to diphosphoglycolyl proline and 6-fluoromevalonate diphosphate, hanging drop vapor diffusion method, using 0.25 M sodium formate and 16% (w/v) PEG 3350, at 20°C
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33molecular docking of inhibitor eriochrome black A, binds to the active site
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33molecular docking of inhibitors 6-fluoromevalonate diphosphate and diphosphoglycolylproline
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33purified enzyme in complex with (R)-5-diphosphomevalonate and adenosine 5'-O-(3-thio)triphosphate or with (R)-5-diphosphomevalonate and ADP, X-ray diffraction structure determination and analysis at 1.5-1.7 A resolution
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33vapour diffusion method, with 0.1 M MES buffer pH 6.5, 20% PEG 5000 MME, 0.1 M NaCl, 1 mM dithiothreitol, and 0.2 M ammonium sulfate
Show all pathways known for 4.1.1.33Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.33wild-type and mutant S192A and D283A ternary complexes with inbhibitor 6-fluoromevalonate 5-diphosphate and ATPgammaS. During the catalytic mechanism, Asp283 correctly positions the mevalonate diphosphate acceptor substrate, while functioning as a catalytic base to abstract the acidic proton found on its C3-hydroxyl. This deprotonation facilitates an in-line transfer of the gamma-phosphoryl from the ATP donor. The Ser 107 side chain is appropriately positioned to hydrogen bond with both the beta- and gamma-phosphoryl groups of ATPgammaS within the ternary structure
Results 1 - 10 of 10