EC Number   |
Reference |
|---|
   3.4.23.1 | - |
35005, 36729, 36733, 36752, 36757, 36764, 36769, 36770 |
| 3.4.23.1 | crystallization in presence of dimethyl sulfoxide. One dimethyl sulfoxide molecule occupies a site on the surface of enzyme interacting with two of its residues. In crystal structure, conformation of enzyme remains unchanged. In solution, dimethyl sulfoxide causes a slight change in secondary structure and complete loss of activity |
667408 |
| 3.4.23.1 | hanging-drop vapour diffusion method, crystal structure of the complex between pepsin inhibitor-3 and the enzyme at 1.75 A and at 2.45 A resolution. In the enzyme-inhibitor complex, the N-terminal beta-strand of pepsin inhibitor-3 pairs with one strand of the active site flap (residues 70-82) of pepsin, thus forming an eight-stranded beta-sheet that spans the two proteins |
653313 |
