EC Number   |
|---|
   3.4.22.66 | by hanging drop vapor diffusion or sitting drop vapor diffusion at room temperature, to 1.5 and 2.2 A resolution |
| 3.4.22.66 | hanging drop vapor diffusion grown at 20°C, at 2.8 A resolution |
| 3.4.22.66 | molecular model of the protease bound with octapeptide FRLEADDG containing a cleavage site of the capsid precursor protein |
| 3.4.22.66 | purified recombinant enzyme bound to inhibitor GC376, X-ray diffraction structure determination and analysis at 2.25 A resolution, molecular replacement |
| 3.4.22.66 | purified recombinant enzyme free and bound to inhibitor (2S)-2-([N-[(benzyloxy)carbonyl]-L-leucyl]amino)-1-hydroxy-3-(2-oxopyrrolidin-3-yl)propane-1-sulfonic acid, X-ray diffraction structure determination and analysis at 1.50 and 1.65 A resolution, respectively, molecular replacement |
| 3.4.22.66 | sitting drop vapor diffusion method, using 18% (w/v) PEG 6000, 10% (v/v) DMSO, 14% methyl-2,4-pentanediol, and 0.12 M Tris-HCl, pH 8.5 |
| 3.4.22.66 | sitting drop vapor diffusion plates at 20°C, 2.25 A resolution structure of Norovirus 3CL protease in complex with a triazole-based macrocyclic inhibitor |
