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EC Number Crystallization (Commentary)
Display the reaction diagram Show all sequences 1.14.11.78structure to 1.8 A resolution
Display the reaction diagram Show all sequences 1.14.11.78structures of Fe(II)-bound ScoE, to 1.45-1.96 A resolution. ScoE has an inducible 2-oxtoglutarate binding site, in which residues arginine-157 and histidine-299 move by approximately 10 A from the surface of the protein into the active site to create a transient 2-oxoglutarate binding pocket. Oxovanadium mimicks Fe(II)
Display the reaction diagram Show all sequences 1.14.11.78structures of iron-loaded ScoE in complex with its substrate and the intermediate show that -NC bond formation involves two cycles of Fe/2OG enzyme catalysis
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