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EC Number Crystallization (Commentary) Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.28complex with tripolyphosphate, to 2.3 A resolution and docking solution of substrate thiamine triphosphate. The thiazole ring of the thiamine forms a stacking interaction with Trp53, and the aminopyrimidine ring lies in a pocket defined by His76, Pro191 and Ile195. The triphosphate moiety occupies a similar position as in the enzyme-tripolyphosphate complex, with interactions involving the side chains of Lys11, Arg55, Arg57, Lys65, Arg125 and Lys193 733393
Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.28hanging drop vapor diffusion method, using 27% (w/v) PEG 3350, 0.1 M Tris (pH 9.0), 0.2 M MgCl2 751047
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