Refine search

Search Crystallization (Commentary)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

Results 1 - 5 of 5
EC Number
Crystallization
Reference
free and ATP-bound enzyme, hanging drop vapor diffusion method, using 0.1 M Tris-HCl pH 7.6, 29% (w/v) PEG 3350, and 0.75 M NaCl (free enzyme) or 1 ml 0.1 M Tris-HCl pH 8.8, 25% (w/v) PEG 3350, and 0.2 M NaCl (ATP-bound enzyme)
sitting-drop vapour diffusion, crystals diffract to a minimum d-spacing of 2 A and belong to either space group C222 or C222(1)
structure determined by NMR spectroscopy
structure of wild-type and E58A mutant human Ap4A hydrolase, to 2.7 and 2.1 A resolution, respectively. Similar to the canonical Nudix fold, human Ap4A hydrolase shows the common alphabetaalpha-sandwich architecture. Two sulfate ions and one diphosphate coordinated with some conserved residues are observed in the active cleft
structures of both apo- and ligand-bound CT771, to 2.6 A and 1.9 A resolution, respectively. The structure shows a alphabetaalpha-sandwich motif with many conserved elements lining the putative Nudix active site
Results 1 - 5 of 5