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generation of 3D models of DCTPP1 and its 5-methyl-dCTP-bound tetramer based on X-ray crystal structure of the tetrameric mouse dCTPase 1, PDB entry 2OIG. The cytosines of substrates 5-methyl-dCTP and dCTP bind deeply into the substrate pocket, which is composed of the residues from the dimer interface, including His38, Trp47, Glu63, Glu66, Trp73, Glu95, Asp98 and Tyr102
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