EC Number   |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
|---|
   3.4.22.59 | 0.0000056 |
- |
acetyl-IETD-aldehyde |
pH 7.5, 25°C |
647423 |
| 3.4.22.59 | 0.000031 |
- |
acetyl-DEVD-aldehyde |
pH 7.5, 25°C |
647423 |
| 3.4.22.59 | 0.000052 |
- |
acetyl-AEVD-aldehyde |
pH 7.5, 25°C |
647423 |
| 3.4.22.59 | 0.00015 |
- |
Zn2+ |
wild type enzyme, in 100 mM HEPES, pH 7.5, 10% (w/v) sucrose, 0.1% (w/v) CHAPS, 20 mM TCEP, and 120 mM NaCl, at 37°C |
732072 |
| 3.4.22.59 | 0.0013 |
- |
cowpox serpin CrmA |
pH 7.5, 25°C |
647423 |
| 3.4.22.59 | 0.003 |
- |
acetyl-WEHD-aldehyde |
pH 7.5, 25°C |
647423 |
| 3.4.22.59 | 0.003 |
- |
Zn2+ |
mutant enzyme E244A, in 100 mM HEPES, pH 7.5, 10% (w/v) sucrose, 0.1% (w/v) CHAPS, 20 mM TCEP, and 120 mM NaCl, at 37°C |
732072 |
| 3.4.22.59 | 0.0046 |
- |
Zn2+ |
mutant enzyme K36A, in 100 mM HEPES, pH 7.5, 10% (w/v) sucrose, 0.1% (w/v) CHAPS, 20 mM TCEP, and 120 mM NaCl, at 37°C |
732072 |
| 3.4.22.59 | 0.007 |
- |
Zn2+ |
mutant enzyme H287A, in 100 mM HEPES, pH 7.5, 10% (w/v) sucrose, 0.1% (w/v) CHAPS, 20 mM TCEP, and 120 mM NaCl, at 37°C |
732072 |
| 3.4.22.59 | 0.0072 |
- |
Zn2+ |
mutant enzyme E244A/H287A, in 100 mM HEPES, pH 7.5, 10% (w/v) sucrose, 0.1% (w/v) CHAPS, 20 mM TCEP, and 120 mM NaCl, at 37°C |
732072 |
