EC Number |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Reference |
---|
1.17.4.4 | -999 |
- |
more |
inhibition kinetics |
674392, 674393 |
1.17.4.4 | -999 |
- |
more |
VKORC1 kinetic model and derivation of the IC50-Ki transformation, overview |
724460 |
1.17.4.4 | 0.00003 |
- |
Difenacoum |
wild-typpe enzyme, pH 7.4, 37°C |
725028 |
1.17.4.4 | 0.00004 |
- |
brodifacoum |
wild-type, pH 7.4, 30°C |
689347 |
1.17.4.4 | 0.00005 |
- |
difethialone |
pH 7.4, 37°C, recombinant enzyme mutants Y139F, and L128Q |
724119 |
1.17.4.4 | 0.00006 |
- |
brodifacoum |
pH 7.4, 37°C, recombinant mutant Y139S enzyme |
724119 |
1.17.4.4 | 0.00007 |
- |
brodifacoum |
pH 7.4, 37°C, recombinant mutant Y139F enzyme |
724119 |
1.17.4.4 | 0.00007 |
- |
Difenacoum |
mutant L128Q, pH 7.4, 37°C |
725028 |
1.17.4.4 | 0.00007 |
- |
Difenacoum |
pH 7.4, 37°C, recombinant mutant L128Q enzyme |
724119 |
1.17.4.4 | 0.00007 |
- |
Difenacoum |
wild-type, pH 7.4, 30°C |
689347 |