EC Number |
Recommended Name |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Structure |
---|
3.4.22.69 | SARS coronavirus main proteinase |
6e-18 |
- |
promazine |
in silico binding studies |
|
3.4.22.69 | SARS coronavirus main proteinase |
8.7e-17 |
- |
lopinavir |
in silico binding studies |
|
3.4.22.69 | SARS coronavirus main proteinase |
2.1e-16 |
- |
N-[3-[(E)-(tert-butoxyimino)methyl]-4-chlorophenyl]-2-methylfuran-3-carboxamide |
in silico binding studies |
|
3.4.21.5 | thrombin |
0.00000000000014 |
- |
RWJ-50353 |
- |
|
3.4.21.5 | thrombin |
0.0000000000011 |
- |
RWJ-51438 |
- |
|
1.5.1.3 | dihydrofolate reductase |
0.00000000002 |
- |
methotrexate |
recombinant enzyme |
|
3.4.21.75 | Furin |
0.0000000000224 |
- |
4-aminomethyl-phenylacetyl-Arg-Tle-Arg-4-aminomethyl-benzamidine |
pH and temperature not specified in the publication |
|
3.4.21.75 | Furin |
0.0000000000337 |
- |
Arg-Arg-Arg-Val-Arg-4-aminomethyl-benzamidine |
pH and temperature not specified in the publication |
|
3.2.2.16 | methylthioadenosine nucleosidase |
0.00000000004 |
- |
5'-4-chloro-phenylthio-4'-deaza-1'-aza-2'-deoxy-1'-(9-methylene)-immucillin-A |
in 100 mM HEPES, 50 mM KCl (pH 7.5), at 25°C |
|
3.2.2.9 | adenosylhomocysteine nucleosidase |
0.000000000047 |
- |
(3R,4S)-4-(4-chlorophenyl-thiomethyl)-1-[(9-deazaadenin-9-yl)methyl]-3-hydroxypyrrolidine |
25°C, pH 7.0, dissociation constant for the equilibrium complex of enzyme-inhibitor following slow-onset inhibition |
|