EC Number   |
Recommended Name |
Ki Value [mM] |
Ki Value maximum [mM] |
Inhibitor |
Structure |
|---|
   3.4.21.98 | hepacivirin |
0.000000094 |
- |
(1aR,5S,8S,9S,10R,22aR)-5-tert-butyl-N-[(1R,2S)-1-[(cyclopropanesulfonyl)carbamoyl]-2-ethenylcyclopropyl]-18,18-difluoro-14-methoxy-9-methyl-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide |
pH and temperature not specified in the publication |
   |
| 3.4.23.16 | HIV-1 retropepsin |
0.000000094 |
- |
N2-acetyl-N-[(2S,3R)-4-[(1,3-benzothiazol-6-ylsulfonyl)(pentyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-L-valinamide |
D30N/L63P/N88D mutant protein |
|
| 3.4.21.75 | Furin |
0.0000000943 |
- |
D-Arg-Arg-Arg-Val-Arg 4-amidinobenzylamide |
pH 7.0, 22°C |
|
 1.5.1.3 | dihydrofolate reductase |
0.000000095 |
- |
methotrexate |
pH 7.4, 25°C, recombinant enzyme |
|
| 2.1.1.45 | thymidylate synthase |
0.000000095 |
- |
methotrexate |
pH 7.4, 25°C, recombinant enzyme |
|
| 3.4.22.16 | cathepsin H |
0.000000095 |
- |
chicken egg white cystatin |
mutant T11_E18del-cathepsin H, pH 6.8, 30°C |
|
| 3.4.21.59 | Tryptase |
0.0000000953 |
- |
6-amidino-2-naphthyl p-guanidinobenzoate dimethane sulfonate |
pH 7.8, 37°C |
|
| 3.2.1.20 | alpha-glucosidase |
0.000000096 |
- |
de-O-sulfonated ponkoranol |
versus the N-terminal subunit N20, pH and temperature not specified in the publication |
|
| 3.4.21.34 | plasma kallikrein |
0.000000097 |
- |
ecotin |
ecotin with mutation H53P in the 50s loop, at room temperature |
|
| 3.4.23.16 | HIV-1 retropepsin |
0.000000097 |
- |
(5S)-N-[(2S,3R)-4-[(1,3-benzothiazol-6-ylsulfonyl)(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]-2-oxo-3-[2-(trifluoromethyl)phenyl]-1,3-oxazolidine-5-carboxamide |
wild type enzyme, in 0.1 M sodium acetate, 1 M sodium chloride, 1 mM EDTA, 1 mM dithiothreitol, 2% (v/v) DMSO, and 1 mg/ml bovine serum albumin, at pH 4.7 and 22°C |
|
