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EC Number Cofactor Commentary Reference
Display the reaction diagram Show all sequences 7.5.2.5ATP - 699542, 750126, 750867, 751032
Display the reaction diagram Show all sequences 7.5.2.5ATP ATP hydrolysis induces conformational changes, the switch region moves and the side chain of H195 flips, ATP binding structure, overview. The H195 is imidazole side chain directly interacts with the gamma-phosphate of ATP. Through a bridging water molecule, the glutamate E163 contacts the beta-phosphate of the nucleotide 752031
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