EC Number   |
Cofactor |
Reference |
|---|
   3.4.21.45 | more |
- |
95497 |
| 3.4.21.45 | more |
a 380000 Da cofactor |
95487 |
| 3.4.21.45 | more |
clumping factor A is shed from the surface of Staphylococcus aureus and binds to factor I. Recombinant clumping factor A and the shed clumping factor A fragment increase factor I cleavage of C3b. Cofactor activity increases in a dose-dependent manner |
699369 |
| 3.4.21.45 | more |
complement component C4bp |
667666 |
| 3.4.21.45 | more |
complement factor C3b and C4b are degraded in the presence of cofactors factor H, C4b-binding protein (C4BP), membrane cofactor protein (MCP) and complement receptor (CR1), respectively |
708380 |
| 3.4.21.45 | more |
complement receptor 1 |
667666 |
| 3.4.21.45 | more |
does not require cofactors for cleavage of synthetic substrates |
652686 |
| 3.4.21.45 | more |
factor H |
667666, 699340 |
| 3.4.21.45 | more |
for cleavage of complement factor C3b or C4b, complement factor I is mixed with C4b-binding protein or membrane cofactor protein or complement receptor 1 or factor H |
708380 |
| 3.4.21.45 | more |
membrane cofactor protein |
667666 |
