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EC Number Cofactor Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.26.5more RNase P RNA is capable of cleaving its substrate in vitro in the absence of any protein cofactor 692711
Display the word mapDisplay the reaction diagram Show all sequences 3.1.26.5more the protein component C5 acts as a cofactor for the catalytic M1 RNA subunit that processes the 5' leader sequence of precursor tRNA. Rpp29, a conserved protein subunit of human RNase P, can substitute for C5 protein in reconstitution assay of M1 RNA activity. Distinct protein folds in two unrelated protein cofactors can facilitate transition from RNA-based to ribonucleoprotein-based catalysis by RNase P 666501
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