EC Number   |
Cofactor |
Reference |
|---|
   2.5.1.46 | NAD+ |
- |
638058, 638059, 638061, 638062, 638063, 638066, 638067, 638071, 638072, 638073, 638074, 638076, 638077, 638078, 638079, 638083, 704694 |
| 2.5.1.46 | NAD+ |
dependent on |
704694 |
| 2.5.1.46 | NAD+ |
each enzyme heterodimer contains two NAD+ binding sites, one housed in the functional catalytic site and the second bound in a remnant dead site that lacks key catalytic residues |
760209 |
| 2.5.1.46 | NAD+ |
induces spermidine binding |
638069 |
| 2.5.1.46 | NAD+ |
not dependent on NAD+ for binding of eIF5A |
638070 |
| 2.5.1.46 | NAD+ |
one enzyme tetramer can bind up to four each of NAD+ and spermidine, the binding of spermidine being dependent on NAD+ |
638068 |
| 2.5.1.46 | NAD+ |
required |
723106, 739026 |
| 2.5.1.46 | NAD+ |
required, Km value is 0.082 mM, kcat is 0.018/s for the heterotetrameric DHS |
738579 |
| 2.5.1.46 | NAD+ |
specific for NAD+ |
638075 |
| 2.5.1.46 | NAD+ |
strict requirement |
638065 |
