EC Number |
Cofactor |
Reference |
---|
1.2.1.39 | more |
enzyme PDH accepts both NAD+ and NADP+ as electron acceptors, but exhibits 86% of its maximal activity with NAD+ but only 5% of its maximal activity with NADP+ |
742786 |
1.2.1.39 | NAD+ |
- |
390293, 390294, 390296, 390298, 390299, 390300, 390301, 686425, 690567, 718, 724020, 725180, 7426, 742786 |
1.2.1.39 | NAD+ |
active with NAD+ and NADP+, preference for NAD+. kcat/Km for NAD+ with propionaldehyde as cosubstrate is 34700 |
670833 |
1.2.1.39 | NAD+ |
N-terminal NAD+-binding domain, comprising residues 1-130 and 159-269, structure analysis, overview |
741787 |
1.2.1.39 | NAD+ |
NADP+ is about 1% as active as NAD+ |
390292 |
1.2.1.39 | NAD+ |
preferred co-substrate |
762624 |
1.2.1.39 | NAD+ |
the most suitable co-substrate is NAD+ |
762619 |
1.2.1.39 | NADH |
- |
742786 |
1.2.1.39 | NADP+ |
- |
742786, 762624 |
1.2.1.39 | NADP+ |
active with NAD+ and NADP+, preference for NAD+. kcat/Km for NADP+ with propionaldehyde is 2460 |
670833 |