EC Number   |
Cofactor |
Reference |
|---|
  1.1.1.430 | more |
Kluyveromyces marxianus strains expressing Pichia stipitis Psxyl1 genes show reversed cofactor specificity, overview |
722891 |
| 1.1.1.430 | more |
most XRs are NADPH-dependent rather than NADH-dependent. CT-XR from Candida tenuis shows a similar preference for both NADH and NADPH |
761599 |
| 1.1.1.430 | NAD(P)H |
- |
700010 |
| 1.1.1.430 | NAD+ |
- |
722891, 761599 |
| 1.1.1.430 | NADH |
- |
722891, 740171, 761599 |
| 1.1.1.430 | NADH |
dual specific xylose reductase (dsXR) has an about 4fold higher specificity for NADH than NADPH |
764945 |
| 1.1.1.430 | NADH |
strongly prefers NADH to NADPH |
695731 |
| 1.1.1.430 | NADH |
transient-state and steady-state kinetic studies of the mechanism of NADH-dependent aldehyde reduction |
696196 |
| 1.1.1.430 | NADH |
using a modified iterative protein redesign and optimization workflow, a sets of mutations is identified that change the nicotinamide cofactor specificity of xylose reductase (CbXR) from its physiological preference for NADPH, to the alternate cofactor NADH |
701106 |
| 1.1.1.430 | NADH |
wild-type enzyme prefers NADPH over NADH. Mutant enzyme K270S/N272P/S271G/R276F shows a 25fold preference toward NADH over NADPH by a factor of about 13fold, or an improvement of about 42fold, as measured by the ratio of the specificity constant kcat/Km coenzyme |
765348 |
