EC Number |
Turnover Number Minimum [1/s] |
Turnover Number Maximum [1/s] |
Substrate |
Reference |
---|
6.3.4.3 | -999 |
- |
more |
- |
1524, 1526 |
6.3.4.3 | -999 |
- |
more |
the Kcat/Km tetrahydrofolate values are 0.03 s/M for the monoglutamate and 0.71 s/M for the pentaglutatmate substrates |
701402 |
6.3.4.3 | 0.39 |
- |
ATP |
27°C, pH 7.0, R97S mutant FTHFS |
649471 |
6.3.4.3 | 0.4 |
- |
formate |
27°C, pH 7.0, R97S mutant FTHFS |
649471 |
6.3.4.3 | 0.99 |
- |
ATP |
27°C, pH 7.0, wild-type FTHFS |
649471 |
6.3.4.3 | 1.13 |
- |
formate |
27°C, pH 7.0, wild-type FTHFS |
649471 |
6.3.4.3 | 2.6 |
- |
(6R,S)-tetrahydrofolate pteroylpentaglutamate |
recombinant enzyme, 30°C |
660817 |
6.3.4.3 | 6.08 |
- |
ATP |
27°C, pH 7.0, wild-type FTHFS |
649471 |
6.3.4.3 | 6.08 |
- |
formate |
27°C, pH 7.0, wild-type FTHFS |
649471 |
6.3.4.3 | 10 |
- |
(6R,S)-tetrahydrofolate pteroyltriglutamate |
recombinant enzyme, 30°C |
660817 |