EC Number   |
Temperature Stability Minimum [°C] |
Temperature Stability Maximum [°C] |
Reference |
|---|
    1.14.16.2 | -999 |
- |
thermal stability of hTH1 is increased by phosphorylation at Ser-40 |
438708 |
| 1.14.16.2 | 4 |
- |
5 h, without stabilizing agent, complete loss of activity |
438698 |
| 1.14.16.2 | 20 |
45 |
60 min |
716647 |
| 1.14.16.2 | 37 |
- |
5 h, stable, catecholamine, N-methyl-norsalsolinol, or norsalsolinol binding increases the thermal stability of tyrosine hydroxylase |
686696 |
| 1.14.16.2 | 37 |
- |
unstable in presence of phosphatidylinositol or NaCl at high concentration, but relatively stable in presence of heparin |
438696 |
| 1.14.16.2 | 40 |
65 |
minimal aggregation occurs for wild type enzyme after heating at 40°C-45 for 60 min. A steep decrease in activity is observed between 40 and 65°C, and a complete loss of activity occurs at temperatures above 70°C |
728715 |
| 1.14.16.2 | 41 |
- |
Tm-value of mutant enzyme T463M is 44.3°C |
660477 |
| 1.14.16.2 | 42 |
- |
or below, all mutant enzymes are stable for at least 1 h |
657679 |
| 1.14.16.2 | 44 |
- |
Tm-value of mutant enzyme T245P is 44.3°C |
660477 |
| 1.14.16.2 | 45 |
- |
in presence of 2% glycerol, enzymes lose activity in time-dependent manner |
657679 |
