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Cloned (Commentary)
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1.14.18.B1
gene KDM6B or JMJD3, quantitative PCR enzyme expression analysis
745509
1.14.18.B1
overexpression of JMJD3 through the transfection of pcDNA3.1-JMJD3 into healthy donor CD4+ T cells leading to an increase in JMJD3 enrichment, a decrease in H3K27me3 enrichment within the ITGAL (CD11a) promoter, and upregulation of CD11a expression, resulting in T and B cell hyperactivity
745948
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