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EC Number Synonyms Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1ATP-independent type I topoisomerase, AtTop1, bcTopo I, bcTopo IIIbeta, bi-subunit topoisomerase I, Bi-subunit topoisomerase IB, Ca-Top1, CrTop1, Dam DNA topoisomerase III, Deoxiribonucleate topoisomerase, Deoxiribonucleic topoisomerase, DNA Top IB, DNA topo I, DNA topoisomerase, DNA topoisomerase 1, DNA topoisomerase I, DNA topoisomerase I alpha, DNA topoisomerase I-B, DNA topoisomerase IB, DNA topoisomerase IIIalpha, DNA topoisomerase type I, EcTOP, ETOP, HssTopoI, HsTop1, hTop1p, hTopI, hTopo, htopo I, hTopo IIIalpha, hTopoI, human DNA topoisomerase I, human Top1, human topo I, human topoisomerase I, Isomerase, deoxiribonucleate topo-, Late protein H6, LdTop1, LdTOP1LS, LdTopIIIbeta, MimiTopIB, MsTopA, MtbTopA, mTopoI, MtTOP1, MttopoI, Nicking-closing enzyme, OjTop1, OlTop1, omega-Protein, OpTop1, PfTopI, PfTopoI, Poxviridae topoisomerase IB, Relaxing enzyme, Reverse gyrase, SsTop3, Swivelase, top I, Top1, TOP1alpha, TOP1mt, Top1p, TopA, TopI, TopIB, topo 1, Topo I, topo IB, topo V, topoI, Topoisomerase, topoisomerase 1, topoisomerase 1alpha, Topoisomerase I, topoisomerase I homolog, topoisomerase IB, topoisomerase III, topoisomerase IIIalpha, topoisomerase IV, topoisomerase V, topoisomerase-I, topoIV, TopR1, TpI, Type I DNA topoisomerase, type I topoisomerase, type IA DNA topoisomerase, type IA topoisomerase, type IB topoisomerase, type IB topoisomerase V, Untwisting enzyme, Vaccinia DNA topoisomerase I, vTopo, yeast DNA topoisomerase I, yeastTop1, YpTOP, YrdD, YTOP - -, 649613, 649801, 651764, 652340, 653375, 653381, 653669, 653935, 661107, 661166, 661946, 662238, 662311, 662426, 662799, 662980, 663213, 663408, 677299, 677937, 678080, 678081, 678082, 678207, 678254, 678377, 678493, 678498, 678603, 679159, 679462, 679762, 680664, 680912, 681288, 681292, 681307, 681403, 681408, 681673, 681674, 681975, 681990, 682013, 682092, 682159, 682161, 682169, 682212, 690782, 690816, 690902, 690972, 691006, 691137, 691221, 691264, 691321, 691568, 691582, 691608, 691619, 691728, 691729, 692246, 692660, 692707, 693067, 693113, 693393, 693400, 693401, 693543, 693562, 693633, 693679, 694248, 694442, 694447, 694448, 694898, 695289, 702077, 702176, 702564, 702579, 702598, 702602, 702620, 702665, 702689, 702810, 702872, 702885, 703153, 705047, 705061, 705597, 705827, 705842, 705973, 705975, 706352, 706656, 713959, 713968, 714188, 714330, 714448, 714463, 714474, 714607, 714643, 714760, 714814, 714871, 714900, 714903, 715605, 715867, 716007, 716378, 716380, 716786, 716834, 716937, 726811, 726921, 726976, 727126, 727127, 727170, 727204, 727268, 727417, 727704, 727774, 727807, 727870, 727922, 728065, 728098, 728137, 728145, 728293, 728393, 728400, 728406, 728558, 728560, 728579, 728639, 728804, 730059, 747038, 747226, 747263, 747474, 747646, 747693, 747698, 747775, 747994, 748151, 748187, 748337, 748358, 748369, 748396, 748397, 748530, 748878, 748912, 749223, 750368, 750702
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1DNA topoisomerase III belongs to the type IA family of DNA topoisomerases 681425
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1vTopo closely related to the human type I topoisomerase (hTopo) 682013
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1EC 5.99.1.2 formerly -
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1hTopoI htopoI readily and very efficiently forms double cleavage complexes after the relaxation of negatively supercoiled plasmid DNA both with recombinant enzyme and with purified htopoI. When topo I is isolated from HeLa S3 cells, a considerable fraction migrates to the same gel electrophoretic position as topo I bearing a covalently bound 13-mer oligonucleotide. This may suggest that double cleavage complexes also form under intracellular conditions 677937
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1Reverse gyrase is a DNA topoisomerase, specific to microorganisms living at high temperatures, which comprises a type IA topoisomerase fused to an SF2 helicase-like module and catalyzes ATP hydrolysis-dependent DNA positive supercoiling -, 727870
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1LdTOP1L large subunit 661734
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1SiRe_1176 locus name -, 728065
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1LdTOP1S small subunit 661734
Display the word mapDisplay the reaction diagram Show all sequences 5.6.2.1topoisomerase IIIbeta subfamily of prokaryotic type IA topoisomerases that are different from the prototypical ecTopo I and ecTopo III-like enzymes -, 681990
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