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EC Number Synonyms Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B43CobB, CobB Sir2 protein, histone desuccinylase, hSIRT5, hSIRT6, lysine desuccinylase, mitochondrial NAD+-dependent lysine deacylase, NAD+ dependent deacetylase, NAD+-dependent protein deacetylase, NAD+-dependent protein deacylase, NAD+-dependent sirtuin deacetylase, nicotinamide adenine dinucleotide-dependent protein deacetylase, Sir2Af1, SIRT5, SIRT5iso1, SIRT5iso2, SIRT5iso3, SIRT5iso4, sirtuin 5, sirtuin 5 deacylase, sirtuin 5 lysine deacylase, sirtuin deacylase, sirtuin-5, zSIRT5 - -, 653891, 702101, 703149, 728857, 728932, 728962, 729138, 729372, 729547, 729556, 729700, 729708, 729732, 729885, 729931, 729967, 729993, 730024, 730049, 730103, 730161, 730203, 730205, 730245, 730347, 730383, 730390, 730406, 730408, 730474, 730680, 730706, 730713, 730900, 730922, 730964, 730974, 731010, 738009, 738110, 738843, 739069, 739445, 755788, 755970, 756010, 756393, 756427, 756522, 756555, 756563, 756680, 757084, 757175, 757184, 757350, 757400, 757590, 758247
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B43SIRT5, SIRT5iso1 SIRT5 isoforms (i.e., SIRT5iso1 and SIRT5iso2) are encoded by the human SIRT5 gene. Their C-termini slightly differ from each other. Although both isoforms contain cleavable mitochondrial targeting signals at their N-termini, it is found that the cleaved SIRT5iso2 is localized mainly in mitochondria, whereas the cleaved SIRT5iso1 is localized in both mitochondria and cytoplasm 729801
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.B43SIRT5iso2 SIRT5 isoforms (i.e., SIRT5iso1 and SIRT5iso2) are encoded by the human SIRT5 gene. Their C-termini slightly differ from each other. Although both isoforms contain cleavable mitochondrial targeting signals at their N-termini, it is found that the cleaved SIRT5iso2 is localized mainly in mitochondria, whereas the cleaved SIRT5iso1 is localized in both mitochondria and cytoplasm. SIRT5iso2 is a primate-specific isoform 729801
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