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EC Number Subunits Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 7.6.2.5heterodimer - 289161
Display the word mapDisplay the reaction diagram Show all sequences 7.6.2.5More cytochrome c maturation requires the ccm operon which encodes eight membrane proteins: the transporter subunits CcmA and CcmB, the CcmC protein interacts directly with heme, CcmE is a periplasmic heme chaperone that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG and CcmH. CcmD is involved in stabilizing the heme chaperone CcmE in the membrane 289166
Display the word mapDisplay the reaction diagram Show all sequences 7.6.2.5More there is a cleft between the N- and C-terminal domains, in which one heme molecule is accommodated with His141 and Tyr240 as axial ligands that are located at the loop regions in the N- and C-terminal domains, respectively. The Fe-N and Fe-O bond distances are 2.2 and 2.1 A, respectively. Heme-binding protein structure comparisons, overview 750302
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