6.2.1.32 | More |
The two half-reactions are cooperatively catalyzed by a large N-terminal domain and a smaller C-terminal domain separated by a flexible linker, the latter undergoes large conformational rearrangements in the course of the catalytic cycle. In PqsA, the adenine ring of the complexed adenylate moiety is sandwiched between the main-chain atoms of G279, S280, and P281 from a loop between beta12 and alpha12 on one side and the side chain of I301 on the opposite side, structure analysis, overview |
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