EC Number   |
Subunits |
Reference |
|---|
   3.1.26.13 | dimer |
- |
715864, 751727 |
| 3.1.26.13 | dimer |
1 * 51000, p51 subunit, + 1 * 66000, p66 subunit, of HIV reverse transcriptase, SDS-PAGE |
716994 |
| 3.1.26.13 | dimer |
HIV-1 RT |
650155 |
| 3.1.26.13 | dimer |
the mature form of reverse transcriptase (RT) is a heterodimer comprising the intact 66-kDa subunit (p66) and a smaller 51-kDa subunit (p51) that is generated by removal of most of the RNase H (RNH) domain from a p66 subunit by proteolytic cleavage between residues 440 and 441 |
752137 |
| 3.1.26.13 | monomer |
1 * 71000, SDS-PAGE of recombinant enzyme with deletion of 204 nucleotides at the 3'-terminus |
643436 |
| 3.1.26.13 | More |
enzyme domain organization, overview |
752137 |
| 3.1.26.13 | More |
monomer/dimer structural variations of helix B-helix D, overview |
751727 |
| 3.1.26.13 | More |
reverse transcriptase RT-RNase H domain structure compare to other RNases H (EC 3.1.13.2), overview |
750633 |
| 3.1.26.13 | More |
RNase H activity is associated with the p66 component of reverse transcriptase |
698685 |
| 3.1.26.13 | More |
the folded structure of the HIV-1 RNase H domain takes the form of a 5-stranded mixed beta-sheet flanked by four alpha helices in an asymmetric distribution, structure comparisons, overview. The p66 subunit is subdivided into three domains: the N-terminal polymerase domain, the C-terminal ribonuclease RNase H domain, and connection domain that links the two functional regions |
716995 |
