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EC Number	Subunits	Commentary	Reference
2.1.1.296	?	x * 48000, SDS-PAGE	728268
2.1.1.296	?	x * 57000, SDS-PAGE	677099
2.1.1.296	More	CMTr2 is divided into two parts: the amino-terminal part with the catalytic RFM domain (CMTr21-430) and the C-terminal part with the non-catalytic RFM domain (CMTr2430-770). The single domains of CMTr2 do not bind the substrate and do not exhibit any cap MTase activity alone or when mixed together as separately purified chains. Thus, CMTr2 requires both RFM domains in a single polypeptide chain for substrate binding and methylation	736863

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Release 2023.1 (January 2023)