EC Number |
Subunits |
Reference |
---|
1.5.1.1 | dimer |
2 * 33312, calculated from sequence |
742531 |
1.5.1.1 | dimer |
2 * 36182, calculated from sequence |
742531 |
1.5.1.1 | dimer |
2 * 37000, SDS-PAGE |
742531 |
1.5.1.1 | dimer |
2 * 40000, SDS-PAGE |
742531 |
1.5.1.1 | dimer |
crystallization data |
674509 |
1.5.1.1 | homodimer |
2 * 33313, sequence calculation, 2 * 37000, recombinant enzyme, SDS-PAGE |
742531 |
1.5.1.1 | homodimer |
2 * 33776, sequence calculation |
743355 |
1.5.1.1 | More |
each subunit contains two distinct domains linked by an alpha-helix. The first domain (a dinucleotide binding domain) binds NADPH or NADP+ and is built around a Rossmann fold-like motif. The second domain is the dimerization domain and is responsible for recognition and binding of thyroid hormones |
743355 |