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Results 1 - 8 of 8
EC Number
Subunits
Commentary
Reference
dodecamer
12 * 29000, two interacting hexamers, analytical ultracentrifugation, 35320.7 Da determined by ESI-MS
hexamer
PdxS exists as a hexamer or dodecamer depending on species and makes a 1:1 complex with PdxT. Pyrococcus horikoshii PdxS forms hexamer in solution. It has a 37 amino acids insertion region, which is found in some archaeal PdxS proteins. This additional insertion perturbs dodecamer formation of Pyrococcus horikoshii PdxS
homododecamer
Pdx1, random association pattern of up to 12 Pdx2 subunits to the Pdx1 dodecamer
homohexamer
6 * 37014, calculated, dynamic light-scattering analysis
homohexamer
gel filtration
More
from crystal structure, the asymmetric unit contains 3 Rv2606c molecules, and the dodecameric structure of the protein can be generated by applying crystallographic I222 symmetry, interfaces for the formation of dodecameric structure, overview
More
the pyridoxal 5'-phosphate synthase complex is made up of 24 protein units assembled like a cogwheel, a dodecameric Pdx1 to which 12 Pdx2 subunits attach. Macromolecular assembly is directed by an N-terminalalpha-helix on the synthase. Interaction with the synthase subunit leads to glutaminase activation, resulting in formation of an oxyanion hole, a prerequisite for catalysis
oligomer
the intact enzyme includes 12 synthase and 12 glutaminase subunits
Results 1 - 8 of 8