EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
    6.4.1.2 | ATP + acetyl-CoA + HCO3- |
- |
Acidianus brierleyi |
ADP + phosphate + malonyl-CoA |
- |
? |
| 6.4.1.2 | ATP + acetyl-CoA + HCO3- |
the bifunctional enzyme also catalyzes the carboxylation of propionyl-CoA. Vmax/Km for carboxylation of propanoyl-CoA is 1.6fold higher than Vmax/Km for carboxylation of acetyl-CoA. Quite specific for ATP. No activity with ADP, AMP, GTP, CTP, UTP, or dTTP (0.2 mM) |
Acidianus brierleyi |
ADP + phosphate + malonyl-CoA |
- |
? |
| 6.4.1.2 | ATP + acetyl-CoA + HCO3- |
key enzyme of 3-hydroxypropionate cycle |
Acidianus brierleyi |
? |
- |
? |
| 6.4.1.2 | ATP + acetyl-CoA + HCO3- |
n-butyryl-CoA (0.5 mM) is carboxylated at 4.6% compared to carboxylation of acetyl-CoA or propionyl-CoA |
Acidianus brierleyi |
? |
- |
? |
| 6.4.1.2 | ATP + propionyl-CoA + HCO3- |
- |
Acidianus brierleyi |
ADP + phosphate + methylmalonyl-CoA |
- |
? |
| 6.4.1.2 | more |
neither succinyl-CoA, palmitoyl-CoA, acetate (plus 0.5 mM CoASH), propionate (plus 0.5 mM CoASH), nor pyruvate is carboxylated by the enzyme |
Acidianus brierleyi |
? |
- |
? |
| 6.4.1.2 | n-butyryl-CoA + HCO3- |
4.6% activity compared to acetyl-CoA or propionyl-CoA |
Acidianus brierleyi |
? |
- |
? |
| 6.4.1.2 | ATP + acetyl-CoA + HCO3- |
- |
Acidianus infernus |
ADP + phosphate + malonyl-CoA |
- |
? |
| 6.4.1.2 | ATP + acetyl-CoA + HCO3- |
no fatty acid synthesis, involved in 3-hydroxypropionate cycle for autotrophic CO2 fixation |
Acidianus infernus |
ADP + phosphate + malonyl-CoA |
- |
? |
| 6.4.1.2 | ATP + acetyl-CoA + HCO3- |
- |
Acidianus infernus So4a / DSM 3191 |
ADP + phosphate + malonyl-CoA |
- |
? |
