EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   5.4.99.17 | (23E)-hydroxysqualene |
- |
Alicyclobacillus acidocaldarius |
rac-(2R)-2-((3aS,5aR,5bR,7aS,11aS,11bR)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysen-3-yl)propanal + rac-(2R)-2-((3aR,5aS,5bS,7aR,11aR,11bS)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysen-3-yl)propanal + rac-2-((3aR,5aS,5bS,7aR,11aR,11bS)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysen-3-yl)prop-2-en-1-ol |
- |
? |
| 5.4.99.17 | (23E)-methylsqualene |
- |
Alicyclobacillus acidocaldarius |
rac-(5R,9S,10R,13R,14R,17S)-4,4,10,13,14-pentamethyl-17-((E)-6-methyloct-5-en-2-yl)-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene + rac-(5R,8S,9S,10R,13S,14S)-4,4,8,10,14-pentamethyl-17-((E)-6-methylocta-1,5-dien-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthrene + rac-(3aR,5aS,5bS,7aR,11aR,11bS,13aS)-3-(but-1-en-2-yl)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysene + rac-2-((3aR,5aS,5bS,7aR,11aR,11bS,13aS)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysen-3-yl)butan-2-ol |
- |
? |
| 5.4.99.17 | (23Z)-hydroxysqualene |
- |
Alicyclobacillus acidocaldarius |
rac-(2R)-2-((3aS,5aR,5bR,7aS,11aS,11bR)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysen-3-yl)propanal + rac-(2R)-2-((3aR,5aS,5bS,7aR,11aR,11bS)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysen-3-yl)propanal + rac-2-((3aR,5aS,5bS,7aR,11aR,11bS)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysen-3-yl)prop-2-en-1-ol + ((9beta,10alpha,13xi,20xi)-20,26-epoxydammar-24-ene) |
- |
? |
| 5.4.99.17 | (23Z)-methylsqualene |
- |
Alicyclobacillus acidocaldarius |
(23Z)-methylsqualene + rac-(3aR,5aS,5bS,7aR,11aR,11bS,13aS)-3-(but-1-en-2-yl)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysene + rac-(3aR,5aS,5bS,7aR,11aR,11bS)-3-((E)-but-2-en-2-yl)-5a,5b,8,8,11a,13b-hexamethylicosahydro-1H-cyclopenta[a]chrysene |
- |
? |
| 5.4.99.17 | (2E)-methylsqualene |
- |
Alicyclobacillus acidocaldarius |
rac-(3aR,5aS,5bS,7aR,11aR,11bS,13aS)-8-ethyl-5a,5b,8,11a,13b-pentamethyl-3-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene |
- |
? |
| 5.4.99.17 | (2E,6E)-farnesol + geraniol |
drimane-8,11-diol is the major product of the wild-type enzyme |
Alicyclobacillus acidocaldarius subsp. acidocaldarius |
drimane-8,11-diol + [(1R,2S)-2-[[(2E)-3,7-dimethylocta-2,6-dien-1-yl]oxy]-2,6,6-trimethylcyclohexyl]methanol + 8-O-geranyl-drimane-8,11-diol + drimenol + albicanol |
- |
? |
| 5.4.99.17 | (2E,6E)-farnesol + H2O |
drimane-8,11-diol is the major product of the wild-type enzyme |
Alicyclobacillus acidocaldarius subsp. acidocaldarius |
8-O-((2E,6E)-farnesyl)-drimane-8,11-diol + drimane-8,11-diol + drimenol + albicanol |
- |
? |
| 5.4.99.17 | (2E,6E)-farnesol + H2O |
- |
Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 |
[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidenedecahydronaphthalen-1-yl]methanol + [(1S,4aS,8aS)-2,5,5,8a-tetramethyl-1,4,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]methanol + (1S,2R,4aS,8aS)-1-(hydroxymethyl)-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol + (1S,2R,4aS,8aS)-1-(hydroxymethyl)-2-O-((2E,6E)-farnesyl)-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol |
- |
? |
| 5.4.99.17 | (2E,6E)-farnesol + n-butanol |
drimane-8,11-diol is the major product of the wild-type enzyme |
Alicyclobacillus acidocaldarius subsp. acidocaldarius |
drimane-8,11-diol + drimenol + albicanol + 8-O-((2E,6E)-farnesyl)-drimane-8,11-diol + drimane-8,11-diol + farnesyl pentyl ether |
- |
? |
| 5.4.99.17 | (3R)-2,3-oxidosqualene + H2O |
- |
Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446 |
3alpha-hydroxyhopene + 3alpha-hydroxyhopanol |
- |
? |
