EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
- |
Mycobacterium tuberculosis |
1-(3-indolyl)glycerol-3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
- |
Saccharolobus solfataricus |
1-(3-indolyl)glycerol-3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
- |
Escherichia coli |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
- |
Pseudomonas aeruginosa |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
- |
Saccharolobus solfataricus |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
- |
Thermococcus kodakarensis |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
- |
Thermus thermophilus |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
the enzyme is involved in tryptophan biosynthesis |
Saccharolobus solfataricus |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
elucidation of the kinetic reaction mechanism, importance of flexible active loops for substrate binding and catalysis by the enzyme, product release is the rate-limiting step of the overall reaction |
Saccharolobus solfataricus |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |
4.1.1.48 | 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate |
tryptophan biosynthetic enzyme |
Saccharolobus solfataricus |
1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O |
- |
? |