EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.6.1.54 | more |
no activity with UDP-N-acetylglucosamine and UDP-3-O-(R)-(3-hydroxymyristoyl)glucosamine, LpxH does not cleave CDP-diacylglycerol |
Escherichia coli |
? |
- |
? |
3.6.1.54 | more |
cytoplasmic cyclophilin PPIB physically interacts with UDP-2, 3-diacylglucosamine hydrolase LpxH |
Azotobacter vinelandii |
? |
- |
? |
3.6.1.54 | UDP-2,3-bis((3R)-3-hydroxymyristoyl)alpha-D-glucosamine + H2O |
a step of lipid A biosynthesis. LpxH is essential in Escherichia coli |
Escherichia coli |
2,3-bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP |
- |
? |
3.6.1.54 | UDP-2,3-bis((3R)-3-hydroxymyristoyl)alpha-D-glucosamine + H2O |
step of lipid A biosynthesis |
Escherichia coli |
2,3-bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP |
- |
? |
3.6.1.54 | UDP-2,3-bis((3R)-3-hydroxymyristoyl)alpha-D-glucosamine + H2O |
step of lipid A biosynthesis. Pseudomonas aeruginosa LpxH catalyzes UDP-2,3-diacylglucosamine hydrolysis in vitro and can substitute for Escherichia coli lpxH in vivo |
Pseudomonas aeruginosa |
2,3-bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP |
- |
? |
3.6.1.54 | UDP-2,3-bis((3R)-3-hydroxymyristoyl)alpha-D-glucosamine + H2O |
Pseudomonas aeruginosa LpxH catalyzes UDP-2,3-diacylglucosamine hydrolysis in vitro and can substitute for Escherichia coli lpxH in vivo |
Pseudomonas aeruginosa |
2,3-bis((3R)-3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP |
- |
? |
3.6.1.54 | UDP-2,3-diacylglucosamine + H2O |
- |
Haemophilus influenzae |
2,3-diacylglucosamine 1-phosphate + UMP |
- |
? |
3.6.1.54 | UDP-2,3-diacylglucosamine + H2O |
the enzyme is selective for UDP-2,3-diacylglucosamine |
Caulobacter vibrioides |
2,3-diacylglucosamine 1-phosphate + UMP |
- |
? |
3.6.1.54 | UDP-2,3-diacylglucosamine + H2O |
the enzyme is selective for UDP-2,3-diacylglucosamine |
Caulobacter vibrioides CB15 |
2,3-diacylglucosamine 1-phosphate + UMP |
- |
? |
3.6.1.54 | UDP-2,3-diacylglucosamine + H2O |
- |
Haemophilus influenzae DSM 11121 |
2,3-diacylglucosamine 1-phosphate + UMP |
- |
? |