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EC Number
Substrates
Commentary Substrates
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Commentary (Products)
Reversibility
3.6.1.31
1-(5-phosphoribosyl)-ATP + H2O
active site structure, overview
Mycobacterium tuberculosis
1-(5-phosphoribosyl)-AMP + diphosphate
-
ir
3.6.1.31
1-(5-phosphoribosyl)-ATP + H2O
phosphoribosyl-ATP pyrophosphohydrolase is the second enzyme in the histidine-biosynthetic pathway, irreversibly hydrolyzing phosphoribosyl-ATP to phosphoribosyl-AMP and pyrophosphate
Mycobacterium tuberculosis
1-(5-phosphoribosyl)-AMP + diphosphate
-
ir
3.6.1.31
1-(5-phosphoribosyl)-ATP + H2O
active site structure, overview
Mycobacterium tuberculosis H37Rv
1-(5-phosphoribosyl)-AMP + diphosphate
-
ir
3.6.1.31
1-(5-phosphoribosyl)-ATP + H2O
phosphoribosyl-ATP pyrophosphohydrolase is the second enzyme in the histidine-biosynthetic pathway, irreversibly hydrolyzing phosphoribosyl-ATP to phosphoribosyl-AMP and pyrophosphate
Mycobacterium tuberculosis H37Rv
1-(5-phosphoribosyl)-AMP + diphosphate
-
ir
3.6.1.31
more
HisE essentiality for growth in vitro
Mycobacterium tuberculosis
?
-
?
3.6.1.31
more
HisE essentiality for growth in vitro
Mycobacterium tuberculosis H37Rv
?
-
?
3.6.1.31
N-1-(5'-phosphoribosyl)-ATP + H2O
-
Salmonella enterica subsp. enterica serovar Typhimurium
N-1-(5'-phosphoribosyl)-AMP + diphosphate
-
ir
3.6.1.31
N-1-(5'-phosphoribosyl)-ATP + H2O
-
Saccharomyces cerevisiae
N-1-(5'-phosphoribosyl)-AMP + diphosphate
-
?
3.6.1.31
N-1-(5'-phosphoribosyl)-ATP + H2O
-
Arabidopsis sp.
N-1-(5'-phosphoribosyl)-AMP + diphosphate
-
?
3.6.1.31
N-1-(5'-phosphoribosyl)-ATP + H2O
enzyme of histidine biosynthesis pathway
Salmonella enterica subsp. enterica serovar Typhimurium
N-1-(5'-phosphoribosyl)-AMP + diphosphate
-
?
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