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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.5.4.3
1-methylguanine + H2O
-
Escherichia coli
1-methylxanthine + NH3
-
?
3.5.4.3
2,6-diaminopurine + H2O
-
Pseudarthrobacter oxydans
xanthine + NH3
-
?
3.5.4.3
2,6-diaminopurine + H2O
the native enzyme shows 107% activity and the recombinant enzyme 98% activity compared to guanine
Blastobotrys adeninivorans
?
-
?
3.5.4.3
2-amino-6-chloropurine + H2O
-
Pseudarthrobacter oxydans
6-chloro-3,9-dihydro-2H-purin-2-one + NH3
-
?
3.5.4.3
2-amino-6-chloropurine + H2O
the native enzyme shows 93% activity and the recombinant enzyme 88% activity compared to guanine
Blastobotrys adeninivorans
6-chloro-9H-purin-2-ol + NH3
-
?
3.5.4.3
2-amino-6-methoxypurine + H2O
-
Pseudarthrobacter oxydans
6-methoxy-3,9-dihydro-2H-purin-2-one + NH3
-
?
3.5.4.3
6-thioguanine + H2O
-
Oryctolagus cuniculus
6-thioxanthine + NH3
-
?
3.5.4.3
6-thioguanine + H2O
-
Kluyveromyces lactis
6-thioxanthine + NH3
-
?
3.5.4.3
6-thioguanine + H2O
-
Sus sp.
6-thioxanthine + NH3
-
?
3.5.4.3
7,8-dihydropterin + H2O
the enzyme exhibits 40fold higher activity for guanine than for 7,8-dihydropterin. Guanine deaminase functions as dihydropterin deaminase in the biosynthesis of aurodrosopterin
Drosophila melanogaster
7,8-dihydrolumazine + NH3
-
?
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