EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.4.24.B17 | 3-deoxy-D-manno-octulosonate transferase + H2O |
3-deoxy-D-manno-octulosonate transferase carries out the attachment of two KDO residues to the lipid A precursor (lipid IVA) to form the minimal essential structure of the lipopolysaccharide (KDO2-lipid A). Thus, FtsH regulates the concentration of the lipid moiety of LPS (lipid A) as well as the sugar moiety (KDO-based core oligosaccharides), ensuring a balanced synthesis of lipopolysaccharide |
Escherichia coli |
? |
- |
? |
3.4.24.B17 | alpha-casein + H2O |
- |
Escherichia coli |
? |
- |
? |
3.4.24.B17 | alpha-casein + H2O |
- |
Escherichia coli AR796 |
? |
- |
? |
3.4.24.B17 | apo-flavodoxin + H2O |
degradation of apo-flavodoxin from Escherichia coli, no degradation of holo-flavodoxin containing non-covalently bound flavin mononucleotide. A mutant flavodoxin carrying a substitution of Tyr94 to Asp (FldYD) with a lower affinity for FMN is efficiently degraded. FtsH is able to initiate degradation of the FldYD moiety even when it is sandwiched by glutathione S-transferase, green fluorescent protein, or both green fluorescent protein and glutathione S-transferase |
Escherichia coli |
? |
- |
? |
3.4.24.B17 | ATP + H2O |
- |
Escherichia coli |
? |
- |
? |
3.4.24.B17 | ATP + H2O |
- |
Escherichia coli AR796 |
? |
- |
? |
3.4.24.B17 | bacteriophage lambdaCII repressor protein + H2O |
- |
Mycobacterium tuberculosis |
? |
- |
? |
3.4.24.B17 | barnase tagged with SsrA tail + H2O |
tail specific degradation |
Escherichia coli |
? |
- |
? |
3.4.24.B17 | beta-casein + H2O |
- |
Bacillus subtilis |
? |
- |
? |
3.4.24.B17 | beta-casein + H2O |
- |
Bacillus subtilis 168 |
? |
- |
? |