EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.4.21.73 | alpha6 integrin + H2O |
alpha6 integrin is present on prostate carcinoma escaping the gland via nerves. Urokinase-dependent cleavage of the laminin binding domain from the prostate tumor cell surface |
Homo sapiens |
? |
- |
? |
| 3.4.21.73 | alpha6 integrin + H2O |
i.e. alpha6p |
Homo sapiens |
? |
- |
? |
| 3.4.21.73 | benzoyl-beta-Ala-Gly-Arg-4-nitroanilide + H2O |
- |
Homo sapiens |
benzoyl-beta-Ala-Gly-Arg + 4-nitroaniline |
- |
? |
| 3.4.21.73 | casein + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.21.73 | Cellular receptor of urokinase-type plasminogen activator + H2O |
cleavage between domains 1 and 2 generating a cell-associated variant of the receptor of urokinase-type plasminogen activator without ligand-binding properties, uPA catalyzed cleavage does not require binding of the protease to the receptor through its epidermal growth factor-like receptor-binding domain, low-molecular weight uPA lacking this domain also cleaves the substrate |
Homo sapiens |
? |
- |
? |
| 3.4.21.73 | D-Glu-Gly-Arg-4-nitroanilide + H2O |
a uPA substrate S-2444 |
Homo sapiens |
D-Glu-Gly-Arg + 4-nitroaniline |
- |
? |
| 3.4.21.73 | D-Ile-Pro-Arg-4-nitroanilide + H2O |
- |
Homo sapiens |
D-Ile-Pro-Arg + 4-nitroaniline |
- |
? |
| 3.4.21.73 | D-Val-Leu-Lys-4-nitroanilide + H2O |
- |
Homo sapiens |
D-Val-Leu-Lys + 4-nitroaniline |
- |
? |
| 3.4.21.73 | epithelial sodium channel gamma subunit + H2O |
of Xenopus laevis ocytes, activation by proteolytic cleavage at 177GR-/-KR180 |
Homo sapiens |
? |
- |
? |
| 3.4.21.73 | GSGRSA + H2O |
- |
Homo sapiens |
GSGR + Ser-Ala |
- |
? |
