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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.4.21.49
Azocoll + H2O
-
Hypoderma lineatum
?
-
?
3.4.21.49
casein + H2O
-
Hypoderma lineatum
?
-
?
3.4.21.49
Collagen + H2O
-
Hypoderma lineatum
?
-
?
3.4.21.49
Collagen + H2O
cleaves native collagen at 3/4 from its N-terminus
Hypoderma lineatum
?
-
?
3.4.21.49
Collagen + H2O
the first cleavage probably occurs between residues 764 and 765 at Pro-Ala and Thr-Ala bonds on the alpha1 and alpha2 chains respectively. Two more bonds would then by cleaved on the alpha1 chain, Ile776-Ala777 and Val782-Val783, and one more on the alpha2-chain, Ser800-Val801
Hypoderma lineatum
?
-
?
3.4.21.49
Collagen + H2O
degrades native collagen in its helical parts
Hypoderma lineatum
?
-
?
3.4.21.49
Collagen + H2O
enzyme functions in degradation of collagen in the connective tissue of the host, so that the larvae of Hypoderma lineatum can feed on the degradation products and migrate
Hypoderma lineatum
?
-
?
3.4.21.49
guinea pig complement C3 + H2O
-
Hypoderma lineatum
?
-
?
3.4.21.49
guinea pig complement C3 + H2O
recombinant enzyme, degradation
Hypoderma lineatum
?
-
?
3.4.21.49
guinea pig complement component C3 + H2O
-
Hypoderma lineatum
?
-
?
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