EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.4.21.42 | 2-aminobenzoyl-GLQRALEI-Lys(dinitrophenol)-NH2 + H2O |
the Abz-GLQRALEI-Lys(Dnp)fluorescence quenched peptide representing the P4-P4' sequence of complement C4 |
Homo sapiens |
? |
- |
? |
| 3.4.21.42 | 2-aminobenzoyl-Gly-Leu-Gln-Arg-Ala-Leu-Glu-Ile-Lys(dinitrophenyl)-NH2 + H2O |
- |
Homo sapiens |
2-aminobenzoyl-Gly-Leu-Gln-Arg + Ala-Leu-Glu-Ile-Lys(dinitrophenyl)-NH2 |
- |
? |
| 3.4.21.42 | 2-aminobenzoyl-Gly-Tyr-Leu-Gly-Arg-Ser-Tyr-Lys-Val-Gly-Lys(dinitrophenyl)-Asp-OH + H2O |
substrate obtained from phage display analysis, 4.7fold higher procession than the natural C1s protease substrate (SLGRKIQI) |
Homo sapiens |
2-aminobenzoyl-Gly-Tyr-Leu-Gly-Arg + Ser-Tyr-Lys-Val-Gly-Lys(dinitrophenyl)-Asp-OH + H2O |
- |
? |
| 3.4.21.42 | 2-aminobenzoyl-Ser-Leu-Gly-Arg-Lys-Ile-Gln-Ile-Lys(dinitrophenyl)-NH2 + H2O |
- |
Homo sapiens |
2-aminobenzoyl-Ser-Leu-Gly-Arg + Lys-Ile-Gln-Ile-Lys(dinitrophenyl)-NH2 |
- |
? |
| 3.4.21.42 | 2-aminobenzoyl-Ser-Val-Ala-Arg-Thr-Leu-Leu-Lys(dinitrophenyl)-NH2 + H2O |
- |
Homo sapiens |
2-aminobenzoyl-Ser-Val-Ala-Arg + Thr-Leu-Leu-Lys(dinitrophenyl)-NH2 + H2O |
- |
? |
| 3.4.21.42 | Ac-Ala-P3-P2-P1-7-amino-4-carbamoylmethylcoumarin + H2O |
a 722-member substrate library with combinations of all proteogenic amino acids at positions P3 and P2 was screened for cleavage, C1s preferred the small polar residues Ser, Ala and Gly at the P2 position and had a broad specificity at P3 position |
Homo sapiens |
? |
- |
? |
| 3.4.21.42 | acetyl-Gly-Lys-naphthyl ester + H2O |
- |
Mesocricetus auratus |
? |
- |
? |
| 3.4.21.42 | Benzoyl-Arg ethyl ester + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.21.42 | benzoyl-beta-Ala-Gly-L-Arg 4-nitroanilide + H2O |
- |
Homo sapiens |
benzoyl-beta-Ala-Gly-L-Arg + 4-nitroaniline |
- |
? |
| 3.4.21.42 | benzoyl-L-Pro-L-Phe-L-Arg 4-nitroanilide + H2O |
- |
Homo sapiens |
benzoyl-L-Pro-L-Phe-L-Arg + 4-nitroaniline |
- |
? |
